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June 1, 2002Journal of Biological ChemistryOpen Access

The Effects of Mutations in Helices 4 and 6 of ApoA-I on Scavenger Receptor Class B Type I (SR-BI)-mediated Cholesterol Efflux Suggest That Formation of a Productive Complex between Reconstituted High Density Lipoprotein and SR-BI Is Required for Efficient Lipid Transport

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Authors

TLTong LiuElectrophysiologyMKMonty KriegerMassachusetts Institute of TechnologyHKHorng-Yuan KanBoston University

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Liu et al. (2002) studied this question.

synapsesocial.com/papers/6a82a08eabc87fc4bf1e11eahttps://doi.org/10.1074/jbc.m112103200
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology1999 · 503 citations
  2. 2Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, an HDL receptor that mediates selective lipid uptake1997 · 223 citations
  3. 3The Efficient Cellular Uptake of High Density Lipoprotein Lipids via Scavenger Receptor Class B Type I Requires Not Only Receptor-mediated Surface Binding but Also Receptor-specific Lipid Transfer Mediated by Its Extracellular Domain1998 · 219 citations
  4. 4A Detailed Molecular Belt Model for Apolipoprotein A-I in Discoidal High Density Lipoprotein1999 · 344 citations
  5. 5Scavenger Receptor Class B, Type I-mediated Uptake of Various Lipids into Cells2001 · 128 citations