Why the study?
Does type 1 diabetes with autonomic neuropathy reduce myocardial perfusion reserve capacity compared to diabetes without autonomic neuropathy and healthy controls?
Population
29 subjects: 9 type 1 diabetic patients with autonomic neuropathy, 10 type 1 diabetic patients without…
Comparison
Dynamic contrast-enhanced magnetic resonance… vs Baseline conditions and comparison across AN+…
Design
Cross-sectional
Authors
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May link autonomic neuropathy to excess CV mortality in type 1 diabetes via impaired reserve; hypothesis-generating and needs longitudinal confirmation.
Does type 1 diabetes with autonomic neuropathy reduce myocardial perfusion reserve capacity compared to diabetes without autonomic neuropathy and healthy controls?
Type 1 diabetic patients with autonomic neuropathy exhibit decreased myocardial perfusion reserve capacity during vasodilatation, which may contribute to their increased cardiovascular mortality.
Taskiran et al. (2002) studied this question.
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