Inhibition by nucleotides of liver microsomal glucose-6-phosphatase.

Ki and Km values are presented in terms of mM concentrations.t Concentrations of cetrimide are in terms of per cent, w/v, of the detergent in microsomal suspensions; lysolecithin and palmityl-Co A were included in assay mixtures at the concentrations indicated.Experiments representative of those employed in evaluating kinetic parameters are described in Figs.2B, 3A, and 3B.