Liver Function in Rheumatoid (Chronic Infectious) Arthritis; Preliminary Report

Article1 January 1937LIVER FUNCTION IN RHEUMATOID (CHRONIC INFECTIOUS) ARTHRITIS; PRELIMINARY REPORTWILLIAM B. RAWLS, M.D., F.A.C.P., SAMUEL WEISS, M.D., F.A.C.P., VERA L. COLLINS, M.D.WILLIAM B. RAWLS, M.D., F.A.C.P.Search for more papers by this author, SAMUEL WEISS, M.D., F.A.C.P.Search for more papers by this author, VERA L. COLLINS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-10-7-1021 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDuring the past few years, much interest has been focused on the subject of decreased dextrose tolerance in acute infectious diseases. Williams and Dick1 found a decreased tolerance in 41 per cent of patients and they also found a similar disturbance in carbohydrate metabolism in experimentally induced toxemia in animals. Their paper contains an excellent review of the literature.Two explanations have been offered for the "diabetic" type of dextrose tolerance curves obtained in these conditions. Some authors1, 2, 3ascribe it to lack of endogenous insulin caused by the functional impairment of the islets of Langerhans, while others4, 5,...References1. WILLIAMSDICK JLGF: Decreased dextrose tolerance in acute infectious diseases, Arch. Int. Med., 1932, l, 801. CrossrefGoogle Scholar2. SWEENEYLACKEY JSRW: The effect of toxemia on tolerance for dextrose, Arch. Int. Med., 1928, xli, 257. CrossrefGoogle Scholar3. SWEENEY JS: Effect of toxemia on the tolerance for dextrose and on the action of insulin, Arch. Int. Med., 1928, xli, 420. CrossrefGoogle Scholar4. LAWRENCEBUCKLEY RDMB: The inhibition of insulin action by toxaemias and its explanation: I. The effect of diphtheria toxin on blood sugar and insulin action in rabbits, Brit. Jr. Exper. Path., 1927, viii, 58. Google Scholar5. SWEENEYBARSHOPLOBELLO JSNLC: Effect of toxemia on the tolerance for dextrose and on the action of insulin, Arch. Int. Med., 1934, liii, 689. CrossrefGoogle Scholar6. SWEENEYBARSHOPLOBELLOROSENTHAL JSNLCRS: Effect of toxemia on the tolerance for dextrose and on the action of insulin, II, Arch. Int. Med., 1934, liv, 381. CrossrefGoogle Scholar7. SOSKINALLWEISSCOHN SMDDJ: Influence of the pancreas and the liver upon the dextrose tolerance curve, Am. Jr. Physiol., 1934, cix, 155. CrossrefGoogle Scholar8. SOSKINALLWEISS SMD: The hypoglycemic phase of the dextrose tolerance curve, Am Jr. Physiol., 1934, cx, 4. CrossrefGoogle Scholar9. TSAIYI CCL: Carbohydrate metabolism of the liver: III. The sugar intake during glucose absorption, Chinese Jr. Physiol., 1934, viii, 273. Google Scholar10. YANNETDARROW HDC: Physiological disturbances during experimental diphtheritic intoxication : II. Hepatic glycogenesis and glycogen concentration of cardiac and skeletal muscle, Jr. Clin. Invest., 1933, xii, 778. YANNET, H., DARROW, D. C., and GOLDFARB, W.: Physiological disturbances during experimental diphtheritic intoxication: III. Respiratory quotients and metabolic rate, Jr. Clin. Invest., 1933, xii, 787. Google Scholar11. SOSKINALLWEISSMIRSKY SMDIA: Interpretation of abnormal dextrose tolerance curves occurring in toxemia in terms of liver function, Arch. Int. Med., 1935, lvi, 927. CrossrefGoogle Scholar12. TADANAKASHIMA : Quoted by Weiss, S.13 Google Scholar13. WEISS S: Diseases of the liver, gallbladder, ducts and pancreas; their diagnosis and treatment, 1935, Paul B. Hoeber Co., New York, p. 180. Google Scholar14. WHIPPLEPEIGHTALCLARK GHTCAH: Tests for hepatic function and disease under experimental conditions: phenoltetrachlorphthalein, Bull. Johns Hopkins Hosp., 1913, xxiv, 343. Google Scholar15. SOSKINMIRSKY SIA: The influence of progressive toxemic liver damage upon the dextrose tolerance curve, Am. Jr. Physiol., 1935, cxii, 649. CrossrefGoogle Scholar16. BOWENLOCKIE BDLM: Chronic atrophic arthritis: the effect of a high carbohydrate diet and insulin on the symptoms and respiratory metabolism, Jr. Lab. and Clin. Med., 1936, xxi, 505. Google Scholar17. DAVIS JS: Protein studies in atrophic (rheumatoid) and hypertrophic arthritis, Jr. Lab. and Clin. Med., 1936, xxi, 478. Google Scholar18. KERRHURWITZWHIPPLE WJSHGH: Regeneration of blood serum proteins. I. Influence of fasting upon curve of protein regeneration following plasma depletion, Am. Jr. Physiol., 1918, xlvii, 356. CrossrefGoogle Scholar19. KERRHURWITZWHIPPLE WJSHGH: Regeneration of blood serum proteins. II. Influence of diet upon curve of protein regeneration following plasma depletion, Am. Jr. Physiol., 1918, xlvii, 370. CrossrefGoogle Scholar20. KERRHURWITZWHIPPLE WJSHGH: Regeneration of blood serum proteins. III. Liver injury alone: liver injury and plasma depletion: the Eck fistula combined with plasma depletion, Am. Jr. Physiol., 1918, xlvii, 379. CrossrefGoogle Scholar21. HOLMANMAHONEYWHIPPLE RLEBGH: Blood plasma protein regeneration controlled by diet. I. Liver and casein as potent diet factors, Jr. Exper. Med., 1934, lix, 251. CrossrefGoogle Scholar22. HOLMANMAHONEYWHIPPLE RLEBGH: Blood plasma protein given by vein utilized in body metabolism. II. A dynamic equilibrium between plasma and tissue proteins, Jr. Exper. Med., 1934, lix, 269. CrossrefGoogle Scholar23. SNELL AM: The effects of chronic disease of the liver on the composition and physicochemical properties of blood: changes in the serum proteins; reduction in the oxygen saturation of the arterial blood, ANN. INT. MED., 1935, ix, 690. Google Scholar24. ROWE AH: The albumin and globulin content of human blood serum in health, syphilis, pneumonia, and certain other infections, with the bearing of globulin on the Wassermann reaction, Arch. Int. Med., 1916, xviii, 455. CrossrefGoogle Scholar25. MYERSKEEFER WKCS: Relation of plasma proteins to ascites and edema in cirrhosis of the liver, Arch. Int. Med., 1935, lv, 349. CrossrefGoogle Scholar26. WELLSYOUMANSMILLER HSJBDG: A formula and nomogram for the estimation of the osmotic pressure of colloids from the albumin and total protein concentrations of human blood sera, Jr. Clin. Invest., 1933, xii, 1103. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication September 24, 1936.From the Arthritis and Gastro-Enterological Clinics of the New York Polyclinic Medical School and Hospital.Read in abstract at the convention of the National Society for the Advancement of Gastroenterology, Atlantic City, N. J., June 5, 1936. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLiver Function Tests in Rheumatoid ArthritisLiver Function Tests in Rheumatoid ArthritisLiver Function Tests in Rheumatoid ArthritisThe Liver in Rheumatoid ArthritisLIVER FUNCTION TESTS IN NONSPECIFIC ARTHRITIS WITH SPECIAL REFERENCE TO HYPERGLOBULINEMIA*BENJAMIN H. ARCHER, M.D.The Advantages of Hepatic Injury and Jaundice in Certain Conditions, Notably the Rheumatic DiseasesRecent Researches on Arthritis and Rheumatism in the United StatesZur Frage der Allergischen Entstehung von Hepatopathieen 1 January 1937Volume 10, Issue 7Page: 1021-1027KeywordsArthritisCarbohydrate metabolismGastroenterology and hepatologyGlucoseHospitalsInfectious diseasesInsulinLiverRheumatoid arthritis ePublished: 1 December 2008 Issue Published: 1 January 1937 PDF downloadLoading ...