Why the study?
Does electrical cardioversion followed by low-dose amiodarone improve outcomes compared to warfarin, quinidine, or no treatment in patients with chronic atrial fibrillation?
Population
Large, hypothetical cohorts of patients with chronic atrial fibrillation followed from 65 to 70 years of age
Comparison
Electrical cardioversion followed by low-dose… vs 1) no treatment; 2) warfarin; 3) electrical…
Design
Other
Follow-up
5 years
Authors
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Amiodarone after cardioversion may lower mortality in chronic AF; leaves open confirmation by randomized trials before practice change.
Does electrical cardioversion followed by low-dose amiodarone improve outcomes compared to warfarin, quinidine, or no treatment in patients with chronic atrial fibrillation?
A Markov decision analysis suggests that cardioversion followed by low-dose amiodarone may offer lower mortality and higher quality-adjusted life-years than warfarin, quinidine, or no treatment in patients with chronic atrial fibrillation.
Dennis L. Disch (1994) studied this question.
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