A substance which inhibits the growth-promoting properties of proteins in rats is present in raw soybeans. The hubstance is non-dialyzable, precipitated by d t, and inactivated by heat. I t appears, therefore, to be a protein, which has been 5homn to be concentrated in the acid-soluble (pH 4.2) fraction of the soybean protein. These results are in agreement with those presented by Ham, Sandstedt, and Musseh for the chick
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Klose et al. (1946) studied this question.