Cryptosporidiosis After Marrow Transplantation: Person-to-Person Transmission and Treatment with Spiramycin

Brief Reports1 August 1984Cryptosporidiosis After Marrow Transplantation: Person-to-Person Transmission and Treatment with SpiramycinANN C. COLLIER, M.D., RICHARD A. MILLER, M.D., JOEL D. MEYERS, M.D.ANN C. COLLIER, M.D., RICHARD A. MILLER, M.D., JOEL D. MEYERS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-101-2-205 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCryptosporidium has received increasing attention as a pathogen in normal as well as immunocompromised persons (1). Infection may be acquired by contact with infected animals, but in many cases no association with either animals or rural settings is apparent, suggesting alternative modes of transmission. Other enteric protozoa may be transmitted by person-to-person contact, such as within daycare centers (2) or by sexual activity (3, 4). We report three cases of cryptosporidiosis that have characteristics of person-to-person transmission. One case occurred in a marrow transplant recipient, who improved during spiramycin treatment.Two cases of cryptosporidiosis occurred in 28-month-old and 16-month-old brothers...References1. CURRENTREESEERNSTBAILEYHEYMANWEINSTEIN WNJWMW. Human cryptosporidiosis in immunocompetent and immunodeficient persons: studies of an outbreak and experimental transmission. N Engl J Med. 1983;308:1252-7. CrossrefMedlineGoogle Scholar2. BLACKDYKESSINCLAIRWELLS RASJ. Giardiasis in daycare centers: evidence of person-to-person transmission. Pediatrics. 1977;60:486-91. MedlineGoogle Scholar3. FELMANRICCIARDI YN. Sexually transmitted enteric diseases. Bull NY Acad Med. 1979;55:533-9. MedlineGoogle Scholar4. OWEN W. Sexually transmitted diseases and traumatic problems in homosexual men. Ann Intern Med. 1980;92:805-8. LinkGoogle Scholar5. Cryptosporidiosis: assessment of chemotherapy of males with acquired immune deficiency syndrome (AIDS). MMWR. 1982;31:589-92. MedlineGoogle Scholar6. Update: treatment of cryptosporidiosis in patients with acquired immunodeficiency syndrome (AIDS). MMWR. 1984;33:117-9. MedlineGoogle Scholar7. Human cryptosporidiosis—Alabama. MMWR. 1982;31:252-4. MedlineGoogle Scholar8. WEISBURGERHUTCHEONYARDLEYROCHEHILLISCHARACHE WDJJWP. Cryptosporidiosis in an immunosuppressed renaltransplant recipient with IgA deficiency. Am J Clin Pathol. 1979;72:473-8. CrossrefMedlineGoogle Scholar9. BAXBYHARTTAYLOR DCC. Human cryptosporidiosis: a possible case of hospital cross infection. Br Med J [Clin Res]. 1983;287:1760-1. CrossrefMedlineGoogle Scholar10. REESECURRENTERNSTBAILEY NWJW. Cryptosporidiosis of man and calf: a case report and results of experimental infections in mice and rats. Am J Trop Med Hyg. 1982;31:226-9. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Fred Hutchinson Cancer Research Center University of Washington Seattle, Washington. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHealthcare-Associated InfectionsGastrointestinal Infections After Solid Organ or Hematopoietic Cell TransplantationCryptosporidium Pathogenicity and VirulenceHealthcare-Associated InfectionsMicroorganisms Responsible for Neonatal DiarrheaRecognition and prevention of hospital-associated enteric infections in the intensive care unitOpportunistic InfectionsHealthcare-Associated InfectionsProphylaxis and ChemotherapyCryptosporidiosis in Saudi Arabia and neighboring countriesMicroorganisms Responsible for Neonatal DiarrheaInfection with Cryptosporidium hominis and reinfection with Cryptosporidium parvum in a transplanted ileum. Case reportInfectious gastro-enteritis: an uncommon cause of diarrhoea in adult allogeneic and autologous stem cell transplant recipientsInactivation of Cryptosporidium parvum oocyst infectivity by disinfection and sterilization processesPulmonary cryptosporidiosis in the acquired immunodeficiency syndromeHuman cryptosporidiosisEtiology and outcome of diarrhea after marrow transplantation: A prospective studyUpdate on the Management of Intestinal Cryptosporidiosis in AIDSInfection Complicating Bone Marrow TransplantationOpportunistic infections: Treatment and developmental therapeutics of cryptosporidiosis and isosporiasisCryptosporidiosisCryptosporidiaPassive transfer of immunity against Cryptosporidium infection in neonatal mice using monoclonal antibodiesAcquired Immunodeficiency SyndromeCoccidian Infections In Aids: Toxoplasmosis, Cryptosporidiosis, and IsosporiasisCryptosporidiosisCryptosporidiosisParasitic DiarrheaNosocomial Transmission and Infection Control Aspects of Parasitic and Ectoparasitic Diseases: Part I. Introduction/Enteric ParasitesGraft-versus-host disease of the intestineCryptosporidiose humaine. Aspects epidemiologiques et cliniquesParasitic DiarrheaProtozoal InfectionsInfection Complicating Bone Marrow TransplantationCryptosporidiosis in PerspectiveHuman CryptosporidiosisSpiramycin in the Treatment of CryptosporidiosisCryptosporidium species, a protean protozoanParasitic diseases of the small intestinal tractAcquired Immunodeficiency Syndrome of ChildhoodCryptosporidium among children with acute diarrhoea in the west of IrelandPulmonary Cryptosporidiosis Occurring in a Bone Marrow Transplant PatientCryptosporidium spp. and cryptosporidiosisImmunofluorescence detection of Cryptosporidium oocysts in fecal smearsQuantification of specific antibody response to Cryptosporidium antigens by laser densitometryCryptosporidiosisCryptosporidiosis. Case report in a health team workerIntestinal and Hepatic Complications of Human Bone Marrow Transplantation. Part IIInfections in bone marrow transplant recipientsAcquired immunodeficiency syndromeProtozoan Infections of Man: Other InfectionsShedding of oocysts by immunocompetent individuals with cryptosporidiosisCryptosporidium species a "new" human pathogen.Cryptosporidiosis in Immunocompetent PatientsCryptosporidiosis as a cause of diarrhea following bone marrow transplantationCryptosporidiosis associated with traveling and giardiasisCase 39-1985PROSPECTIVE STUDY OF ACQUISITION OF CRYPTOSPORIDIUM, GIARDIA LAMBLIA, AND GASTROINTESTINAL ILLNESSAcquired Immune Deficiency Syndrome: A Perspective for the Medical PractitionerCryptosporidiosis in Immunocompetent PatientsDetection of Cryptosporidium oocysts in sputum during screening for mycobacteriaInfection in Relation to Thoracic TransplantationCryptosporidium 1 August 1984Volume 101, Issue 2Page: 205-206KeywordsBone marrowCryptosporidiosisCryptosporidiumHuman sexual behaviorInfectious diseasesMicrobiologyOrthopedicsPathogensResearch laboratoriesTransplantation Issue Published: 1 August 1984 PDF downloadLoading ...