Elaboration of the A ring of phomazarin by the Conrad‐Limpach approach has been shown to be possible in the case of a protected hydroquinone substrate. However similar condensations using a suitably substituted naphthoquinone gave a lactam instead of the expected benzoquinolone. Attempts to annulate simplified models of the A‐B rings with the appropriate diene have also been successful albeit in low yield.
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Guay et al. (1987) studied this question.
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