Das trans‐decalingerüst als Abstandshalter für axial konfigurierte Diamine: Herstellung eines phosphatbindenden Bis(guanidins)

trans ‐Decalin as a Spacer for Axially Configurated Diamines: Preparation of a Phosphate Binding Bis(guanidinium) Compound A new type of bis(guanidinium) compound 2 is described which was prepared from trans ‐decalin spacers bearing nitrogen substituents in axial positions. Starting from 2, 7‐dimethoxynaphthalene, a sequence of three Birch reductions produced gram amounts of the saturated intermediate and established the stereochemistry of the decalin framework. Guanidinium salt 2a turned out to be a good receptor molecule for phosphoric acid diester anions. However, the catalytical influence on phosphoryl transfer reactions is only weak. magnified image