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January 1, 1996European Journal of Neuroscience

Potassium Channel mRNA Expression in Prevertebral and Paravertebral Sympathetic Neurons

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Population

Rat sympathetic ganglia (superior cervical ganglion, coeliac ganglion, and superior mesenteric ganglion)

Comparison

Quantitative analysis of eighteen different… vs Comparison between superior cervical ganglion…

Design

Preclinical

Authors

JDJane E. DixonState University of New YorkDMDavid McKinnonState University of New York

Discussion

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Implication

Kv subunit patterns in rat sympathetic ganglia merit functional studies; leaves open translation to human autonomic cardiovascular regulation.

Structured PICO

P
Population
Rat sympathetic ganglia (superior cervical ganglion, coeliac ganglion, and superior mesenteric ganglion)
I
Intervention
Quantitative analysis of eighteen different voltage-activated potassium channel genes using an RNase protection assay
C
Comparator
Comparison between superior cervical ganglion (SCG) and two prevertebral sympathetic ganglia (coeliac ganglion and superior mesenteric ganglion)
O
Outcome
Relative level of potassium channel mRNA expressionsurrogate

The study identifies differential expression of specific voltage-activated potassium channel genes between prevertebral and paravertebral sympathetic neurons in rats.

Cite This Study

Dixon et al. (1996) studied this question.

synapsesocial.com/papers/6a82b3f7abc87fc4bf1e180ehttps://doi.org/10.1111/j.1460-9568.1996.tb01179.x
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