Editorials1 November 1986Infectious Diarrheas: Acute, Chronic, and IatrogenicMARTIN J. BLASER, M.D.MARTIN J. BLASER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-105-5-785 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn both health and disease, the lumen of the gut is an intricate ecosystem that yields its mysteries grudgingly. Despite this complexity, the last decade has produced a virtual revolution in the ability of microbiologists to identify enteric pathogens. Among these new agents being identified are bacteria, includingCampylobacter jejuniand several of its cousins,Clostridium difficile, Yersinia enterocolitica, newVibriospecies, and cytotoxin-producing strains ofEscherichia coli;protozoans, notablyCryptosporidium, Blastocysts, andIsosporaspecies; and viruses such as atypical rotaviruses and enteric adenoviruses. In this issue, Holmberg and colleagues (1, 2) from the Centers for Disease Control provide further...References1. HOLMBERGSCHELLFANNING SWG. Aeromonas intestinal infections in the United States. Ann Intern Med. 1986;105:683-9. LinkGoogle Scholar2. HOLMBERGWAHSMUTHHICKMAN-BRENNERBLAKEFARMER SIFPJ. Plesiomonas enteric infections in the United States. Ann Intern Med. 1986;105:690-4. LinkGoogle Scholar3. TAYLORECHEVERRIABLASER DPM. Polymicrobial aetiology of travellers' diarrhoea. Lancet. 1985;1:381-3. CrossrefMedlineGoogle Scholar4. DRAKEGILCHRISTWASHINGTONHUIZEUGAVAN SCOY AMJKR. Diarrhea due to Campylobacter fetus subspecies jejuni: a clinical review of 63 cases. Mayo Clin Proc. 1981;56:414-23. Google Scholar5. BLASERWELLSFELDMANPOLLARDALLEN MJRRJ. Campylobacter enteritis in the United States: a multicenter study. Ann Intern Med. 1983;98:360-5. LinkGoogle Scholar6. GUERRANTSHIELDSTHORSONSCHORLINGGRÖSCHEL RDSJD. Evaluation and diagnosis of acute infectious diarrhea. Am J Med. 1985;78(6B):91-8. CrossrefGoogle Scholar7. RADETSKY M. Laboratory evaluation of acute diarrhea. Pediatr Infect Dis. 1986;5:230-8. CrossrefGoogle Scholar8. WILLIAMSLOHRGUERRANT EJR. Acute infectious diarrhea: II. Diagnosis, treatment and prevention. Pediatr Infect Dis. 1986;5:458-65. CrossrefGoogle Scholar9. PAIGORDONSIMSBRYAN CRHL. Sporadic cases of hemorrhagic colitis associated with Escherichia coli 0157:H7: Clinical, epidemiologic, and bacteriologic features. Ann Intern Med. 1984;101:738-42. LinkGoogle Scholar10. BONNERCOKERBERRYMANPOLLOCK JACH. Spectrum of vibrio infections in a Gulf Coast community. Ann Intern Med. 1983;99:464-9. LinkGoogle Scholar11. READKREJSREADSANTA ANAMORAWSKIFORDTRAN NGMCSJ. Chronic diarrhea of unknown etiology. Gastroenterology. 1980;78:264-71. CrossrefMedlineGoogle Scholar12. READREADKREJSHENDLERDAVISFORDTRAN NMGRGJ. A report of five patients with large-volume secretory diarrhea but not evidence of endocrine tumor or laxative abuse. Dig Dis Sci. 1982;27:193-201. CrossrefGoogle Scholar13. FITZGERALDCLARK JJ. Chronic diarrhea. Pediatr Clin North Am. 1982;29:221-31. CrossrefGoogle Scholar14. HOLMESSALTER KR. Irritable bowel syndrome—a safe diagnosis? Br Med J [Clin Res]. 1982;285:1533-4. CrossrefMedlineGoogle Scholar15. BLASER M. Nonspecific proctocolitis in northeastern Scotland—another view [Letter]. Gastroenterology. 1984;86(5 pt 1): 1003-4. Google Scholar16. GRACEYBURKEROBINSON MVJ. Aeromonas-associated gastroenteritis. Lancet. 1982;2:1304-6. CrossrefGoogle Scholar17. GEORGENAKATATHOMPSONWHITE WMJM. Aeromonasrelated diarrhea in adults. Arch Intern Med. 1985;145:2207-11. CrossrefGoogle Scholar18. SINCLAIRBRUNTMOWAT TPN. Nonspecific proctocolitis in northeastern Scotland: a community study. Gastroenterology. 1983;85:1-11. CrossrefGoogle Scholar19. OSTERHOLMMACDONALDWHITE MKK. An outbreak of a newly recognized chronic diarrhea syndrome associated with raw milk consumption. JAMA. 1986;256:484-90. CrossrefMedlineGoogle Scholar20. MARTINHOBERMAN DL. A point source outbreak of chronic diarrhea in Texas: no known exposure to raw milk [Letter]. JAMA. 1986;256:469. CrossrefMedlineGoogle Scholar21. GIANNELLA R. Chronic diarrhea in travelers: diagnostic and therapeutic considerations. Rev Infect Dis. 1986;8(suppl 2):S223-6. CrossrefGoogle Scholar22. STRUM W. Nine months of diarrhea after a Mexican meal. Hosp Pract [Off]. 1986;21:54-6. Google Scholar23. SHAPIROTOWNSENDROSNERKASS MTBE. Use of antimicrobial drugs in general hospitals: patterns of prophylaxis. N Engl J Med. 1979;301:351-5. CrossrefGoogle Scholar24. BAUMKENNEDYKNAPPFAICH CDDG. Drug Utilization in the U.S.—1983: Fifth Annual Review. Rockville, Maryland: Division of Drug Experience, Food and Drug Administration; 1985. Google Scholar25. BOHNHOFFMILLER MC. Enhanced susceptibility to Salmonella infections in streptomycin-treated mice. J Infect Dis. 1962;111:117-27. CrossrefGoogle Scholar26. ADLERANDERSONBORINGNAHMIAS JRJA. A protracted hospital-associated outbreak of salmonellosis due to a multiple-antibiotic-resistant strain of Salmonella indiana. J Pediatr. 1970;77:970-5. CrossrefGoogle Scholar27. VAN DER WAAIJ D. Colonization resistance of the digestive tract: clinical consequences and implications. J Antimicrob Chemother. 1982;10:263-70. CrossrefMedlineGoogle Scholar28. ROSENTHAL S. Exacerbation of salmonella enteritis due to ampicillin. N Engl J Med. 1969;280:147-8. CrossrefGoogle Scholar29. HOLMBERGOSTERHOLMSENGERCOHEN SMKM. Drug-resistant Salmonella from animals fed antimicrobials. N Engl J Med. 1984;311:617-22. CrossrefGoogle Scholar30. RILEYCOHENSEALS LMJ. Importance of host factors in human salmonellosis caused by multiresistant strains of Salmonella. J Infect Dis. 1984;149:878-83. CrossrefGoogle Scholar31. RYANNICKELSMCDONALD CMR. Contamination of pasteurized milk with multiple drug-resistant Salmonella: the largest Salmonella outbreak in United States history [Abstract 252]. In: Program and Abstracts of the Twenty-fifth Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, D.C.: American Society for Microbiology; 1985. Google Scholar32. BARTLETT J. Antibiotic-associated pseudomembranous colitis. Rev Infect Dis. 1979;1:530-9. CrossrefGoogle Scholar33. BORRIELLOLARSONWELCHBARCLAYSTRINGERBARTHOLOMEW SHAFMB. Enterotoxigenic Clostridium perfringens: a possible cause of antibiotic-associated diarrhoea. Lancet. 1984;1:305-7. CrossrefGoogle Scholar34. SUGIYAMA H. Animal models for the study of infant botulism. Rev Infect Dis. 1979;1:683-8. CrossrefGoogle Scholar35. CHIACLARKRYANPOLLACK JJCM. Botulism in an adult associated with food-borne intestinal infection with Clostridium botulinum. N Engl J Med. 1986;315:239-41. CrossrefMedlineGoogle Scholar36. WEISSMANGANGAROSA JE. Nosocomial Shigellosis at a Custodial Institution in Donelson, Tennessee. Atlanta: Center for Disease Control; 1973. (Epi-73-90-2.) Google Scholar37. FRETER R. Experimental enteric Shigella and Vibrio infections in mice and guinea pigs. J Exp Med. 1956;104:411-8. CrossrefGoogle Scholar38. KUNIN C. Antibiotic resistance—a world heath problem we cannot ignore [Editorial]. Ann Intern Med. 1983;99:859-60. LinkGoogle Scholar39. MURRAYRENSIMERDUPONT BEH. Emergence of high-level trimethoprim resistance in fecal Escherichia coli during oral administration of trimethoprim or trimethoprim-sulfamethoxazole. N Engl J Med. 1982;306:130-5. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1986Volume 105, Issue 5Page: 785-787KeywordsEscherichia coliOral administration Issue Published: 1 November 1986 PDF DownloadLoading ...
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