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January 6, 2001Organic Letters

Iodination of Organic Substrates with Halide Salts and H₂O₂ Using an Organotelluride Catalyst

Michael R. Detty Donald E. Higgs Marina I. Nelen

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Abstract

[figure: see text] Organotelluride 1 is a water-soluble catalyst for the oxidation of iodide with hydrogen peroxide in pH 6 phosphate buffer. In two-phase systems, organic substrates are efficiently iodinated using 0.8 mol % of catalyst. Water-soluble substrates are iodinated without an organic cosolvent.

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Detty et al. (2001) studied this question.

synapsesocial.com/papers/6a82c45a8aa2f088808d65b9 https://doi.org/10.1021/ol0068142

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