Palladium–catalyzed cross–coupling reactions of allylic alcohols and arylboronic acids in water are described. The reactions proceeded smoothly in water at reflux using catalytic amounts of [Pd(allyl)Cl] 2 and PPh 3 . Addition of a catalytic amount of a base allowed the reaction to proceed even at lower temperatures.
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Manabe et al. (2005) studied this question.
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