Key result
A 64-year-old man with primary duodenal dedifferentiated liposarcoma underwent pylorus-preserving pancreaticoduodenectomy but died 60 days postoperatively due to complications.
Case Report (n=1)
No
Primary duodenal dedifferentiated liposarcoma is an extremely rare and aggressive neoplasm that requires careful differential diagnosis using histology, immunohistochemistry, and MDM2 amplification.
Rare duodenal dedifferentiated liposarcoma resection carries high perioperative mortality risk; leaves optimal management undefined pending larger series.
BACKGROUND: hybridization (FISH). Herein, we report an unusual case of DDLPS arising from the duodenum. CASE SUMMARY: FISH, leading to the final diagnosis of DDLPS. Following surgery, the patient was treated in the intensive care unit due to peritonitis, and died 60 d after surgery. CONCLUSION: To the best of the authors' knowledge, this is the first case of primary duodenal DDLPS in Korea and the third case in the English-language literature. Care must be taken not to misdiagnose DDLPS as another high-grade tumor. Liposarcoma should be in the differential diagnosis list.
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Kim et al. (2022) conducted a case report in Primary duodenal dedifferentiated liposarcoma (n=1). Pylorus-preserving pancreaticoduodenectomy was evaluated on Patient outcome. A 64-year-old man with primary duodenal dedifferentiated liposarcoma underwent pylorus-preserving pancreaticoduodenectomy but died 60 days postoperatively due to complications.
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