The ACS1 gene, encoding acetyl-coenzyme A synthetase, was mapped genetically at the left arm of chromosome I between pURA3 and PYK1 at 19 and 28 cM respectively. Comparison with the physical map defined a recombinational 'hot-spot' in this region in addition to the one between CDC24 and PYK1.
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Steensma et al. (1993) studied this question.
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