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The tetrazole ring is an important pharmacophore. It is a structural component in many drugs, drug candidates (or lead compounds) and various biochemical reagents. This review summarizes data on the use of tetrazoles in biomedicine published in the last 10 – 15 years and also views on the nature of their biological effects. The prospects for the development of new biologically active substances containing a tetrazolyl pharmacophore are analyzed. The bibliography includes 263 references.
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Popova et al. (2019) studied this question.
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