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June 1, 2002Journal of Biological ChemistryOpen Access

Protein Kinase Cε-dependent Regulation of Cystic Fibrosis Transmembrane Regulator Involves Binding to a Receptor for Activated C Kinase (RACK1) and RACK1 Binding to Na+/H+ Exchange Regulatory Factor

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Authors

CLCarole M. LiedtkeCase Western Reserve UniversityCYChris YunEmory UniversityNKNicole KyleCase Western Reserve University

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Liedtke et al. (2002) studied this question.

synapsesocial.com/papers/6a82d84b92c19701ea21eb3ehttps://doi.org/10.1074/jbc.m201917200
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA1989 · 7,491 citations
  2. 2Regulation of cystic fibrosis transmembrane conductance regulator single-channel gating by bivalent PDZ-domain-mediated interaction2001 · 212 citations
  3. 3Binding Specificity for RACK1 Resides in the V5 Region of βII Protein Kinase C2001 · 186 citations
  4. 4The RACK1 Signaling Scaffold Protein Selectively Interacts with the cAMP-specific Phosphodiesterase PDE4D5 Isoform1999 · 311 citations