Key result
Left ventricular hypertrophy in very elderly hypertensive patients is associated with a significantly higher prevalence of three-vessel coronary artery disease (24.2% vs 6.9%) compared to those without LVH.
Why the study?
The relationship between left ventricular hypertrophy and coronary artery disease in very elderly patients with hypertension was investigated.
Does left ventricular hypertrophy correlate with the severity of coronary artery disease in very elderly patients with hypertension?
Observational (n=120)
No
Does left ventricular hypertrophy correlate with the severity of coronary artery disease in very elderly patients with hypertension?
Absolute Event Rate: 24.2% vs 6.9%
p-value: p=0.03
In very elderly hypertensive patients, the presence of left ventricular hypertrophy is associated with more severe, multi-vessel, and diffuse coronary artery disease.
LVH may signal need for CAD evaluation in very elderly hypertensives; leaves open prospective validation of screening utility.
Objective: To investigate the relationship between left ventricular hypertrophy (LVH) and coronary artery disease in the very elderly (over 80 years old) patients with hypertension. Methods: One hundred twenty cases of very elderly patients with hypertension admitted to our hospital from March 2018 to December 2020 were selected and divided into two groups: the LVH group and the non-LVH group, all of whom were older aged over 80 years, including 62 patients in the LVH group and 58 patients in the non-LVH group. All patients underwent cardiac color Doppler ultrasound examination, 24-hour dynamic ECG examination, and coronary angiography or coronary CTA examination. The clinical data of the two groups were analyzed statistically. Results: There were significant differences in the number of diseased vessels, degree of coronary stenosis and vascular calcification between the two groups (P<0.05). Moreover, the results of risk factors for the degree of coronary artery disease in the two groups showed that the history of diabetes, 2hPG and LVH were independent risk factors for the three-vessel disease, while the history of LVH, FPG and alcohol intake were independent risk factors for diffuse lesions, but there was no statistical difference in the correlation between them and the degree of coronary stenosis. Conclusion: LVH is an independent risk factor for coronary artery stenosis and calcification in the very elderly patients with hypertension, but there is no statistical difference in the correlation between LVH and the degree of coronary stenosis. doi: https://doi.org/10.12669/pjms.37.5.4135 How to cite this:Sun JH, Liu XK, Zhang Q, Zhang QH. Study on the correlation between Left Ventricular Hypertrophy and Coronary Artery disease in the very elderly patients with hypertension. Pak J Med Sci. 2021;37(5):1382-1386. doi: https://doi.org/10.12669/pjms.37.5.4135 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Sun et al. (2021) conducted an observational in Hypertension (n=120). Left ventricular hypertrophy vs. Non-LVH was evaluated on Three-vessel coronary artery disease (p=0.03). Left ventricular hypertrophy in very elderly hypertensive patients is associated with a significantly higher prevalence of three-vessel coronary artery disease (24.2% vs 6.9%) compared to those without LVH.
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