Poly‐ L ‐arginine was prepared by the guanidization of poly‐ L ‐ornithine with 1‐guanyl‐3,5‐dimethylpyrazole. The poly‐ L ‐ornithine was derived from poly‐δ, N ‐trifluroacetyl‐ L ‐ornithine by removal of the blocking groups under mild basic conditions (1 M piper‐idine).
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Ariely et al. (1966) studied this question.
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