Key result
Norovirus P particle formation increases the immunogenicity of the P protein and plays a crucial role in the immune enhancement of the vaccine.
Highlights the importance of P particle formation in enhancing the immunogenicity of norovirus vaccines.
As a commentary on a recently published paper in Immunology, this article summaries the principle of norovirus P particle as a promising vaccine against noroviruses. It emphasizes the importance of P particle formation in the immune enhancement of the vaccine and methods for production/verification of high quality P particles which may be easily neglected by researchers.
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Tan et al. (2012) studied this question. Norovirus P particle formation increases the immunogenicity of the P protein and plays a crucial role in the immune enhancement of the vaccine.
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