A helping strand: A method to selectively form copper nanoparticles in solution using double-stranded DNA has been developed. The size of the nanoparticles is controlled by the length of the dsDNA template, and single-stranded DNA did not act as a template (see scheme). Single-stranded overhangs in dsDNA were used to prepare a nanostructure in which two metallized dsDNA segments were linked together by a nonmetallized rigid linker.
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Rotaru et al. (2010) studied this question.
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