We present a magnetic multiplexed assay technology which encodes the identities of target biomolecules according to the moment of magnetic beads to which they are attached. An active digital technique based on a microfabricated magnetoresistive ring-shaped sensor is demonstrated, which can distinguish the magnetic moments of micron-sized superparamagnetic beads. We propose that this development is key to combining nonvolatile magnetic labeling with biochemical libraries for high-throughput bioassays and rapid multiplexed detection.
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Llandro et al. (2007) studied this question.
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