Answers are grounded in this paper and cite their sources.
Previous surveys among Indians with RA have shown a significant association with HLA DR4 in North India and with HLA DR1 in the UK. We studied a migrant Indian population in South Africa to determine their genetic associations with RA. A group of 121 unrelated RA patients from three communities (Hindi, Muslims and Tamils) were studied. The Muslims showed a significant association with DR4 but the Hindi and Tamils showed a significant association with DR10. This survey shows that the Indian community is a heterogenous group regarding their HLA associations with RA and different associations are noted in the various communities.
No takes yet. Share an insight, caveat, or question.
Mody et al. (1994) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: