Kaposi's Sarcoma, Chronic Ulcerative Herpes Simplex, and Acquired Immunodeficiency

Recently, increasing numbers of young homosexual men with a fulminant form of Kaposi's sarcoma have been described.¹,²We report herein a case of a young homosexual man with Kaposi's sarcoma, chronic perianal and nasolabial ulcerating herpes simplex infection, oral candidiasis, and immunodeficiency, presumably acquired. Report of a Case In December 1980, a 22-year-old Hispanic homosexual man residing in New York City was hospitalized for a six-month history of weight loss and fever. Physical examination disclosed a man with cachexia, oral mucosal white pseudomembranous plaques, generalized adenopathy, and splenomegaly. Physical examination findings were otherwise normal. Laboratory studies disclosed the following values: WBCs, 3,200/cu mm; hemoglobin, 10g/dL; ESR, 109 mm/hr; hepatitis B antigen test, negative; and hepatitis B antibody test, positive. Pharyngeal culture for yeasts showed the presence ofCandida albicans. Chest x-ray films showed a nonspecific infiltrate in the right upper lobe. However,Pneumocystis cariniiwas not detected in the