Fishing for enantiomers: A novel kinetic resolution of racemic alcohols capable of two-point binding makes use of silanes with silicon-centered chirality. This strategy is based on a diastereoselective dehydrogenative silicon–oxygen coupling under copper catalysis (see scheme). The resolving silane is completely recovered without erosion of stereochemical information at silicon.
No takes yet. Share an insight, caveat, or question.
Rendler et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: