Evidence for Sexual Transmission of Human T Lymphotropic Virus Type II

Letters1 January 1992Evidence for Sexual Transmission of Human T Lymphotropic Virus Type IIBrian Hjelle, MD, S. Cyrus, MT (SBB), S. G. Swenson, MT (SBB)Brian Hjelle, MDSearch for more papers by this author, S. Cyrus, MT (SBB)Search for more papers by this author, S. G. Swenson, MT (SBB)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-116-1-90 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors: We know little about the routes of spread of human T lymphotropic virus type II (HTLV-II). Direct evidence for spread of HTLV-II has been documented only for transfusion (1, 2), but epidemiologic evidence supports its transmission sexually and via contaminated needles in drug users (3, 4). Antibodies to HTLV-II are usually detected by enzyme-linked immunosorbent assay (ELISA) and Western blot reagents prepared from HTLV-I-infected cells.We have studied family members of patients with documented HTLV-II infection to ascertain the frequency with which close family contacts become infected. Serologic testing of the approximately 4000 donations per month to...References1. HjelleMillsMertzSwenson BRGS. Transmission of HTLV-II via blood transfusion. Vox Sang. 1990;59:119-22. CrossrefMedlineGoogle Scholar2. DoneganBuschGalleshawShawMosley EMJGJ. Transfusion of blood components from a donor with human T-lymphotropic virus type II (HTLV-II) infection. Ann Intern Med. 1990;113:555-6. LinkGoogle Scholar3. TedderShansonJeffriesCheingsong-PopovClaphamDalgleish RDDRPA. Low prevalence in the UK of HTLV-I and HTLV-II infection in subjects with AIDS, with extended lymphadenopathy, and at risk for AIDS. Lancet. 1984;2:125-8. CrossrefMedlineGoogle Scholar4. LeeSwansonShortyZackRosenblattChen HPVJJI. High rate of HTLV-II infection in seropositive IV drug abusers in New Orleans. Science. 1989;244:471-5. CrossrefMedlineGoogle Scholar5. HjelleMillsSwensonMertzKeyAllen BRSGCS. Incidence of hairy cell leukemia, mycosis fungoides, and chronic lymphocytic leukemia in first known HTLV-II-endemic population. J Infect Dis. 1991;163:435-40. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Brian Hjelle, MD; S. Cyrus, MT (SBB); S. G. 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