Key result
Pregnancy managed with prophylactic dalteparin in 16 women with previous iliac vein stents resulted in 0% hemorrhagic complications, recurrent VTE, or stent damage up to 12 months postpartum.
Why the study?
Whether iliac vein stents affect pregnancy or are affected by pregnancy was rarely reported in the literature.
Does prophylactic dalteparin prevent recurrent thrombosis and stent complications during pregnancy in women with previous iliac vein stenting for DVT?
Observational (n=16)
Does prophylactic dalteparin prevent recurrent thrombosis and stent complications during pregnancy in women with previous iliac vein stenting for DVT?
Pregnancy in women with prior iliac vein stenting for DVT appears safe and does not compromise stent integrity when managed with prophylactic dalteparin.
Hypothesis-generating for managed pregnancy after iliac stenting with dalteparin; leaves open confirmation in prospective cohorts.
BACKGROUND: Whether iliac vein stents affect pregnancy or whether they will be affected by pregnancy was rarely reported in the literature. The aim of this study was to report our experience of pregnancy in women who received thrombolysis and stenting for a previous deep vein thrombosis (DVT). METHODS: 16 patients with previous stenting for treatment of acute left iliofemoral DVT who had subsequent pregnancies were identified. Patient demographic information and outcomes were recorded. Duplex scanning and venography were performed as scheduled to evaluate the patency of stents in perinatal period and at 12 months after delivery. RESULTS: None of the patients had a hemorrhagic complication and recurrent venous thromboembolism during their pregnancies and postpartum. No stent compression/occlusion and structural damage occurrence in all patients during follow-up. CONCLUSION: Pregnancy managed with prophylactic dalteparin resulted in no re-thrombotic events or structural damage to the iliac stents and did not appear to negatively affect pregnancy outcomes.
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Zhou et al. (2023) conducted an observational in Pregnancy with previous catheter-directed thrombolysis and stenting for acute left iliofemoral deep vein thrombosis (n=16). Pregnancy managed with prophylactic dalteparin in women with previous iliac vein stents was evaluated on Hemorrhagic complication, recurrent venous thromboembolism, and stent compression/occlusion or structural damage. Pregnancy managed with prophylactic dalteparin in 16 women with previous iliac vein stents resulted in 0% hemorrhagic complications, recurrent VTE, or stent damage up to 12 months postpartum.
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