Light-induced acceleration of specific binding between CEACAM-5 and antibodies for early detection of colorectal cancer

levels of CEACAM-5 at high sensitivity under a laser beam irradiation of several hundred mW for several minutes at a defocused condition equivalent to the microchannel width. Specifically, we discovered the existence of nanoscale CEACAM-5 aggregates related to the sensitivity of the MF-LAC-SYS, using dynamic light scattering and electron microscopy. The results will potentially pave the way for a platform using unconventional immunoassays for liquid biopsy and blood proteomics.