Key result
Physical activity and cognitive training are linked to moderate improvements in global cognition and executive function in patients with mild cognitive impairment, though evidence for slowing progression to dementia is mixed.
Why the study?
Does non-pharmacological treatment reduce symptoms and prevent progression to dementia in patients with mild cognitive impairment?
Does non-pharmacological treatment reduce symptoms and prevent progression to dementia in patients with mild cognitive impairment?
In the absence of solid pharmacological options, non-pharmacological interventions like cardiovascular risk reduction and lifestyle modifications remain key strategies for managing mild cognitive impairment.
May support cognitive gains from activity and training in MCI; leaves open dementia prevention effects.
Mild cognitive impairment, also considered a “pre-dementia” stage, has a prevalence of 10-20% in people aged 65 or more. The risk increases with age and is higher in the male gender. Nearly 10% to 15% of MCI patients progress to a diagnosis of probable AD each year, relative to only 1% to 2% of the general elderly population. The importance of successfully treatment of this early illness phases cannot be overstated. At the moment there is no solid pharmacological evidence of a drug that can improve symptoms of mild cognitive impairment or delay its progress to dementia. The current treatment options include: reducing cardiovascular risk factors and prevention of stroke. Social engagement, aerobic exercise, mental activity may help reduce further cognitive decline. In this review we take a closer look at the impact of nonpharmacological treatment on symptom reduction and progression of mild cognitive impairment to dementia.
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Pavel et al. (2018) conducted a review in Mild Cognitive Impairment (MCI). Non-pharmacological treatment (physical activity and cognitive training) vs. Control/No intervention was evaluated on Symptom reduction and progression to dementia. Physical activity and cognitive training are linked to moderate improvements in global cognition and executive function in patients with mild cognitive impairment, though evidence for slowing progression to dementia is mixed.
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