NA‐872 is a bromhexine metabolite. Thirty‐two patients with Sjögren's syndrome were treated with 15 mg × 3 daily for 3 weeks, without effect, compared to placebo, judged by Schirmer I‐test, break up time, Bijsterveld score, cornea sensitivity and bisquit eating time.
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Manthorpe et al. (1981) studied this question.
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