A simple procedure for studying sterol biosynthesis in cell-free homogenates of Candida albicans is described. The activities of some imidazole-containing antifungals (tioconazole, clotrimazole, econazole, ketoconazole and miconazole) as inhibitors of sterol C-14 demethylation have been determined using this technique.
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M. S. Marriott (1980) studied this question.
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