A novel transient multi-physics model using an arbitrary Lagrange-Euler mesh successfully simulated mitral valve closure and fluid-structure interaction during systole.
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Novel FSI model simulates mitral valve closure with physiologic strains; extends computational tools but leaves open clinical validation.
A transient multi-physics model of the mitral heart valve has been developed, which allows simultaneous calculation of fluid flow and structural deformation. A recently developed contact method has been applied to enable simulation of systole (the stage when blood pressure is elevated within the heart to pump blood to the body). The geometry was simplified to represent the mitral valve within the heart walls in two dimensions. Only the mitral valve undergoes deformation. A moving arbitrary Lagrange-Euler mesh is used to allow true fluid-structure interaction (FSI). The FSI model requires blood flow to induce valve closure by inducing strains in the region of 10-20%. Model predictions were found to be consistent with existing literature and will undergo further development.
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Espino et al. (2012) studied this question.
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