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This report gives the evidence for statements (Montagu, 1957(Montagu, , 1959) ) that a basic catechol compound other than noradrenaline and adrenaline is present in considerable amounts in the brains of different animals, and that it is probably 3hydroxytyramine.Human brain contained, in addition, 3,4-dihydroxyphenylalanine and an acidic catechol compound.The presence of 3-hydroxytyramine in brain was also reported in 1957 by Carlsson, Rosengren, Bertler & Nilsson (see Bertler & Rosengren, 1959), and has since been confirmed by others (see the Discussion section).
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Katharine A. Montagu (1963) studied this question.
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