Braden score for early mortality risk assessment in critically ill intensive care patients with multiple organ dysfunction syndrome

Multiple organ dysfunction syndrome (MODS) is a clinical syndrome characterized by the simultaneous or sequential dysfunction of two or more organs. This condition can result in prolonged hospital stays, high in-hospital mortality rates, and an increased financial burden. Therefore, the identification of risk factors for death is crucial because timely intervention can enhance patient prognosis and reduce mortality rates. This study aimed to investigate the relationship between the Braden Score and in-ICU mortality in patients with MODS. This retrospective study analyzed patients with MODS from the MIMIC-III and MIMIC-IV databases. A multiple-variable logistic model was used to investigate the relationship between initial admission Braden Score and all-cause ICU mortality. The study included 37,981 patients with MODS, with a median age of 68 years (60% male). The in-ICU mortality rate was 8.6%. Upon admission, the Braden score showed a negative association with the mortality which remained consistent even after multivariate adjustment (adjusted OR = 0.87, 95% CI 0.85-0.88, P < 0.0001). This study discovered a significant negative correlation between Braden Score and in-ICU mortality in patients with MODS.