Detailed histological analysis of ovaries obtained from 25 women by ovariectomy for medical reasons demonstrated that the degeneration of the cyclic corpus luteum is a long process, taking several cycles. The ages of the various regressing corpora lutea were identified to permit classification of the side of ovulation during the preceding 4 or 5 cycles. In the 25 women studied, with regular menstrual cycles of 28 +/- 3 days (48 cycles), ovulation occurred most often (87.6%) in an alternating manner.
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A. Gougeon (1984) studied this question.
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