Massive exercise-induced rhabdomyolysis with CK > 1.4 million can be successfully managed with aggressive IV hydration without the development of acute renal failure.
May support aggressive hydration in extreme rhabdomyolysis without AKI; hypothesis-generating, should not change practice.
Rhabdomyolysis induced by exercise is a very well known entity, several cases has been reported in the literature related with strenuous activities, weight lifting, marathon running, overexertion in an untrained person, knee bends, etc. We reported an interesting case of exercise-induced rhabdomyolysis in a 25 year old Hispanic male, after resuming his regular physical activity, with the highest creatine kinase described in the literature, successfully treated with aggressive hydration only and no complications.
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Casares et al. (2008) studied this question.
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