Why the study?
Is there a correlation between tumor size, pulmonary artery pressure, and NYHA functional class in patients with left atrial myxoma?
Is there a correlation between tumor size, pulmonary artery pressure, and NYHA functional class in patients with left atrial myxoma?
In patients with left atrial myxoma, tumor size correlates positively with pulmonary artery pressure and NYHA functional class, and surgical excision leads to significant clinical and hemodynamic improvement.
Hypothesis-generating in left atrial myxoma; larger prospective studies required before any practice implications.
To examine the correlation between the size of left atrial myxoma, the degree of pulmonary hypertension and the patient's New York Heart Association (NYHA) functional class, the records of 29 surgically treated patients with left atrial myxoma were reviewed. Of 29 patients, 23 were catheterized before surgery. As the preoperative NYHA functional class advanced, the preoperative mean pulmonary artery pressure (mmHg) was seen to increase. Moreover, the weight of the excised myxoma also correlated well with the preoperative pulmonary artery pressure value. In five patients inserted with a Swan-Ganz catheter, the mean pulmonary artery pressure decreased immediately after tumour excision. Postoperatively, the average NYHA class of the 29 patients significantly improved. These results confirmed the positive correlation between the size of the tumour, the pulmonary artery pressure, and NYHA class in patients with left atrial myxoma.
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Toshiaki Nakano (1996) studied this question.
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