Why the study?
Delayed extubation after cardiac surgery is associated with mortality, and it was unclear whether spinal anesthesia combined with general anesthesia reduces mechanical ventilation time compared to general anesthesia alone.
Does spinal anesthesia combined with general anesthesia reduce mechanical ventilation time and increase operating room extubation frequency in patients undergoing cardiac surgery?
Does spinal anesthesia combined with general anesthesia reduce mechanical ventilation time and increase operating room extubation frequency in patients undergoing cardiac surgery?
The addition of spinal anesthesia to general anesthesia in cardiac surgery significantly increases the rate of operating room extubation and reduces overall mechanical ventilation time.
May facilitate earlier extubation after cardiac surgery; hypothesis-generating and requires randomized confirmation.
INTRODUCTION: The delayed extubation of patients undergoing mechanical ventilation (MV) in the postoperative period of cardiac surgery (CS) is associated with mortality. The adoption of spinal anesthesia (SA) combined with general anesthesia in CS influences the orotracheal intubation time (OIT). This study aims to verify if the adoption of SA reduces the time of MV after CS, compared to general anesthesia (GA) alone. METHODS: Two hundred and seventeen CS patients were divided into two groups. The GA group included 108 patients (age: 56±1 years, 66 males) and the SA group included 109 patients (age: 60±13 years, 55 males). Patients were weaned from MV and, after clinical evaluation, extubated. RESULTS: In the SA group, considering a 13-month period, 24% of the patients were extubated in the operating room (OR), compared to 10% in the GA group (P=0.00). The OIT was lower in the SA group than in the GA group (SA: 4.4±5.9 hours vs. GA: 6.0±5.6 hours, P=0.04). In July/2017, where all surgeries were performed in the GA regimen, only 7.1% of the patients were extubated in the OR. In July/2018, 94% of the surgeries were performed under SA, and 64.7% of the patients were extubated in the OR (P=0.00). The OIT on arrival at the intensive care unit to extubation, comparing July/2017 to July/2018, was 5.3±5.3 hours in the GA group vs. 1.7±3.9 hours in the SA group (P=0.04). CONCLUSION: The adoption of SA in CS increased the frequency of extubations in the OR and decreased OIT and MV time.
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Elmiro et al. (2020) studied this question.
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