Why the study?
Is nadolol once daily as effective as propranolol four times daily for improving physical performance and reducing symptoms in patients with angina?
Is nadolol once daily as effective as propranolol four times daily for improving physical performance and reducing symptoms in patients with angina?
Nadolol once daily is as effective as propranolol four times daily for managing angina and improving physical performance.
May simplify angina regimens via once-daily dosing; leaves open confirmation versus contemporary standards.
1 Improvement in physical performance, based on exercise tolerance, self-assessed work and physician-rated functional capacities, is proposed as a measure of efficacy of anti-anginal therapy in the rehabilitation of the cardiac patient. 2 Improved physical performance parallels changes in frequency of anginal attacks and a nitroglycerin requirements following beta-blocker therapy. 3 Nadolol (a beta-blocker), given once daily is as effective as propranolol, given four times daily as an anti-anginal agent.
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LING et al. (1979) studied this question.
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