Answers are grounded in this paper and cite their sources.
We report about modification of poly( N -vinylpyrrolidone) (PVP) with monofunctional β-cyclodextrin (βCD) via click-chemistry. The modification was carried out by copper(I)-catalyzed microwave-assisted Huisgen-type cycloaddition of 3-propargyl- N -vinylpyrrolidone ( 2a ) and mono(6-azido-6-deoxy)-β-cyclodextrin ( 3 ). We synthesized a copolymer ( 5 ) carrying CD moieties which has the same composition as the applied molar ratio of monomers. Complexation experiments of the obtained polymer ( 5 ) with phenolphthalein (PP) showed a lower binding constant compared to βCD caused by sterical effects of the polymer coil.
No takes yet. Share an insight, caveat, or question.
Trellenkamp et al. (2010) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: