Dosimetric Impact on Bone Marrow Sparing with Dual Energy Vmat in Treatment of Cervical Cancer

Background: To investigate the dosimetric impact on bone marrow sparing using VMAT of dual arc using dual energy in treatment of cervical cancer. Methods: Twenty patients with cervical cancer were chosen retrospectively. Bone marrow was contoured to all the cases. Four VMAT (Volumetric Modulated Arc Therapy) plans were generated like Dual Arc (DA) with 6MV energy of x-ray photon, DA with 10MV, DA of dual energy with (6MV and 10MV) and DA of dual energy with (6MV and 15MV) and were optimized using similar planning objectives and dose calculation was done using Monte Carlo algorithm. The dosimetric results were compared to find significance difference using Repeated Measures ANOVA with significance level set at 5%.