Cytochrome P-450 denotes collectively all forms of membranebound hemoprotein associated with NADPH-dependent monooxygenase activities and capable of binding CO when reduced."PI-450" is defined arbitrarilv as that polycyclic aromatic inducible form associated most closely with polycyclic aromatic inducible aryl hydrocarbon hvdroxylase activity."P-448" is defined arbitrarily as that polycyclic aromatic inducible form having a Soret peak shifted maximally to the blue when reduced and combined with CO.
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Nebert et al. (1980) studied this question.
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