Why the study?
Does radiofrequency ablation improve left ventricular ejection fraction in a patient with Wolff-Parkinson-White Syndrome presenting as cardiomyopathy?
Does radiofrequency ablation improve left ventricular ejection fraction in a patient with Wolff-Parkinson-White Syndrome presenting as cardiomyopathy?
Radiofrequency ablation can lead to normalization of left ventricular ejection fraction in patients with cardiomyopathy secondary to Wolff-Parkinson-White Syndrome.
May support ablation in WPW cardiomyopathy; hypothesis-generating case report requiring prospective validation.
A 31-year-old male was referred for a stress test due to worsening palpitations and chest pressure. His clinic 12-lead electrocardiogram was normal. At the time of his stress test, his pre-exercise electrocardiogram revealed an intermittent short PR interval with a delta wave. This pattern resolved during exercise, but in recovery he experienced paroxysms of supraventricular tachycardia. Imaging revealed low left ventricular ejection fraction. Given the diagnosis of Wolff-Parkinson-White Syndrome, he underwent radiofrequency ablation. His cardiomyopathy was presumed to be secondary to his Wolff-Parkinson-White, and an echocardiogram a few months later showed normalization of his left ventricular ejection fraction.
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Young et al. (2021) studied this question.
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