ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe gem Effect. III. The Influence of 3-Mono- and 3-gem Substitution on the Acid Dissociation Constants of Glutaric Acid. A Comparison of the Sensitivity of [UNK]pKa of Dicarboxylic Acids and the Rate of Ring Closure of Their Monoesters to the Intramolecular Distance Separating Carboxyl FunctionsThomas C. Bruice and William C. BradburyCite this: J. Am. Chem. Soc. 1965, 87, 21, 4851–4855Publication Date (Print):November 1, 1965Publication History Published online1 May 2002Published inissue 1 November 1965https://pubs.acs.org/doi/10.1021/ja00949a032https://doi.org/10.1021/ja00949a032research-articleACS PublicationsRequest reuse permissionsArticle Views97Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
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Bruice et al. (1965) studied this question.