BACKGROUND AND PURPOSE: This review characterizes the current state of knowledge of high-density lipoprotein (HDL) in relation to stroke. SUMMARY OF REVIEW: HDL has anti-atherosclerotic and anti-inflammatory properties and is an important component in atherosclerosis. Serum HDL-cholesterol levels are inversely related to heart disease and stroke risk. There are various established and experimental treatments which can raise serum HDL cholesterol and improve its function. CONCLUSIONS: HDL is an emerging target for atherosclerotic stroke treatment with the potential to dramatically impact the care of stroke patients.
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Sanossian et al. (2007) studied this question.
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