Why the study?
The study evaluated whether normobaric hyperoxia modulates acral-skin vasoreactivity and thermosensitivity to localised cooling in normothermic and mildly hypothermic states.
Does normobaric hyperoxia modulate finger vasomotor and thermoperceptual responses to local cold in normothermic and mildly hypothermic individuals?
Does normobaric hyperoxia modulate finger vasomotor and thermoperceptual responses to local cold in normothermic and mildly hypothermic individuals?
Normobaric hyperoxia aggravates finger cold-induced vasoconstriction and pain sensation in normothermic individuals, but this effect is overridden by generalized vasoconstriction during mild hypothermia.
May heighten cold sensitivity during normobaric oxygen use; leaves open clinical relevance in hypothermic states.
AIM: breathing would modulate acral-skin vasoreactivity and thermosensitivity to localised cooling. METHODS: ) hand cold (8 °C water) provocation, while immersed to the chest either in 35.1 (0.4)°C (normothermic trial) or in 21.0 (0.1)°C (hypothermic trial) water. Finger temperature, circulatory and perceptual responses were monitored. RESULTS: During the normothermic trial, hyperoxia augmented the cold-induced drop in finger temperature, and attenuated the rewarming (P = 0.03). Hyperoxia also enhanced the sensation of pain (P = 0.04). During the hypothermic trial, hyperoxia did not modify finger temperature, circulatory and perceptual responses to cold (P > 0.05). CONCLUSION: In normothermia, hyperoxia aggravates finger cold-induced vasoconstriction and pain sensation. In mild hypothermia, however, any hyperoxia-evoked influence on finger vasomotion and thermonociception is overridden by the generalised vasoconstriction and thermal discomfort instigated by whole-body cooling.
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Keramidas et al. (2025) studied this question.
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