Why the study?
Does surgical closure of atrial septal defect improve hemodynamic parameters in adult patients?
Does surgical closure of atrial septal defect improve hemodynamic parameters in adult patients?
Surgical closure of ASD in adults significantly improves hemodynamics and reduces pulmonary artery pressure without progression of obstructive pulmonary vascular changes.
May support hemodynamic benefit from adult ASD closure; leaves open need for randomized confirmation before practice change.
To assess the long-term cardiac status after surgical closure of atrial septal defects (ASD) in adults, 20 of 62 patients over 20 years of age who underwent surgey during past 15 years participated in this study and underwent cardiac catheterization examination. They were 7 male and 13 female with an average age of 46.2 years, and a mean follow-up period was 23.7 months. Mean PA pressure decreased significantly from 22.1±8.9 to 15.9± 3.6mmHg, while Qp/Qs and mean-Pp/Ps significantly changed from 3.65±1.58 to 1.09±0.14 and from 0.19±0.18 to 0.10±0.05 respectively. It was suggested that the obstructive pulmonary vascular change had not progressed so far, and all patients obtained an improvement in the quality of life. Therefore surgical closure for elderly patients with ASD is recommended unless they have major operative risk or severe pulmonary vascular disease with Eisenmenger's syndrome.
No takes yet. Share an insight, caveat, or question.
Konagai et al. (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: