The metabolism, motility and fertilizing capacity of spermatozoa from the caput, corpus and cauda epididymidis were examined. Motility increased from 3% to almost 50% from caput to cauda. Caput sperm were almost infertile, when inseminated into the uterus. Corpus and cauda sperm fertilized ova in 54 and 60% (respectively) of females, but the number of offspring was below our average colony litter size. Caffeine, 10 mM, had no effect on any of the sperm characteristics measured. No teratogenic effects or long‐term effects on fertility of the offspring were seen.
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Paz et al. (1978) studied this question.
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