A comparative study of susceptibility of primary monkey kidney cells, Hep 2 cells and HeLa cells to a variety of faecal viruses

A comparative study of the susceptibility of monkey kidney, Hep 2 and HeLa cells to enteroviruses and adenoviruses is made. It seems that this Hep 2 cell line is as effective as the monkey kidney cells in their susceptibility to vaccine strains of polioviruses and far better than monkey kidney cells in their susceptibility to strains of ECHO 6 and ECHO 11 from clinical material. It is as effective as, or slightly better than, HeLa cells for the isolation of adenoviruses. It also compares favourably with monkey kidney cells for the isolation of other enteroviruses. We are most grateful to Glaxo Laboratories Ltd. for the supplies of monkey kidney cells used in this investigation.