INTRODUCTION 311 CENT~,OMEmC ONA 312 Budding Yeast 312 Fission Yeast 313 Mammalian Centromeres 314 STRUCTURAL ORGANIZATION OF D A IN THE CELL 316 Chromatin Structure of Fungal Centromeres 316 Structural Features of Mammalian Centromeres 317 CENTROMERIC PROTEINS 318 Centromere-Associated Antigens 318 Histones 319 Centromere DNA-Binding Factors 320 Satellite DNA-Binding Proteins 324 REGULATION AND ASSEMBLY OF CENTROMERIC COMPONENTS 326 Chromosome Copy Control Mutants 327 Chromosome Fidelity Mutants 329 EVOLUTION OF THE KINETOCHORE 329
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Schulman et al. (1991) studied this question.